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Sunday, October 6, 2013

31 for 21 Challenge: Day Six. Statistics

This is a blog entry from 10/11/2012:


1 in 691 babies, in the U.S., are born with Down Syndrome yearly.

Reportedly, 88% of all cases arise from the mother's chromosome 21.
8% arise from the father's chromosome.
2% arise from mitotic errors after fusion.

Translocation Down Syndrome account for approximately 4-5% of all DS cases.

Nothing 'causes' Down Syndrome - it's no-one's fault.


66-89% of individuals with Down Syndrome have some level of hearing loss.

Chances of developing pneumonia are 62x higher in people with Down Syndrome.

The risk of leukemia is 15-20x higher in individuals with DS.

Seizures occur in 3-13% of people with Down Syndrome.

Approximately 50% of children with DS have congenital heart disease.

100% of people with DS will develop signs of Alzheimer's past the age of 35.



92% of pregnancies with a prenatal diagnosis of DS are terminated.

80% of babies with Down Syndrome are born to women under the age of 35.
Mom's AgeRisk for trisomy 21 (Down syndrome)Risk for all trisomies
201 in 1,6671 in 526
211 in 1,4291 in 526
221 in 1,4291 in 500
231 in 1,4291 in 500
241 in 1,2501 in 476
251 in 1,2501 in 476
261 in 1,1761 in 476
271 in 1,1111 in 455
281 in 1,0531 in 435
291 in 1,0001 in 417
301 in 9521 in 384
311 in 9091 in 384
321 in 7691 in 323
331 in 6251 in 286
341 in 5001 in 238
351 in 3851 in 192
361 in 2941 in 156
371 in 2271 in 127
381 in 1751 in 102
391 in 1371 in 83
401 in 1061 in 66
411 in 821 in 53
421 in 641 in 42
431 in 501 in 33
441 in 381 in 26
451 in 301 in 21
461 in 231 in 16
471 in 181 in 13
481 in 141 in 10
491 in 111 in 8

There are approximately 6,000 Down Syndrome diagnoses, in the U.S., each year.

There are more than 400,000 people in the U.S. living with Down Syndrome.

Odds of having a child with Down Syndrome increase based on mother's age as shown here:

Frequency of Down Syndrome
Per Maternal Age


Age (years) Frequency of Fetuses with Down
Syndrome to Normal Fetuses
at 16 weeks of pregnancy
Frequency of Live Births of
Babies with Down Syndrome
to Normal Births
15 - 19 ---- 1 / 1250
20 - 24 ---- 1 / 1400
25 - 29 ---- 1 / 1100
30 - 31 ---- 1 / 900
32 ---- 1 / 750
33 1 / 420 1 / 625
34 1 / 325 1 / 500
35 1 / 250 1 / 350
36 1 / 200 1 / 275
37 1 / 150 1 / 225
38 1 / 120 1 / 175
39 1 / 100 1 / 140
40 1 / 75 1 / 100
41 1 / 60 1 / 85
42 1 / 45 1 / 65
43 1 / 35 1 / 50
44 1 / 30 1 / 40
45 and older 1 / 20 1 / 25


When we first learned about Josiah having Down Syndrome, these numbers meant more.  We took them more seriously.  The numbers, at times, frightened us.  That isn't true any more.  Josiah is just a little boy.  He's OUR little boy.  He's one of three!  Having children can be risky.  Being 'sure' about their future can be speculative.  We couldn't be happier with the family we have.  We couldn't ask for better children.  If we could go back and do it all over again.....

.....we wouldn't change a thing.


"Give me a firm place to stand, and I will move the earth."
- Archimedes

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